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Title: Antineoplastic Testosterone Molecular Complex
Authors: PAIVA, Gerson Silva
Issue Date: 2-Dec-2010
Publisher: World Intellectual Property Organization (WIPO)
Abstract: The present invention relates to an antineoplastic testosterone molecular complex comprising a testosterone molecular chain (1), an antineoplastic drug and a molecular bridge or molecule. The present compound is characterised in that it comprises a testosterone molecule (1) chemically bonded to a commercially available antineoplastic drug, such as daunorubicin or doxorubicin (2), cisplatin (3), carboplatin (4) or cisplatin-berenil (5), by a molecular bridge such as carbamate (6) or by an N',N-disuccinimidyl-carbonate molecule (7). The molecular complex "guides" the anti-cancer drug directly to the tumour, enabling the drug to have a selective effect on the prostate, and thus preventing effects on healthy tissues, since this type of cancer requires large amounts of testosterone to develop.
URI: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2010108251
https://repositorio.ufpe.br/handle/123456789/61751
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