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Título : Molecular compound comprising an acridine molecule chemically linked to a carboxylic group, which can be used for the selective destruction of solid tumour cells
Autor : CARVALHO, Marcos de Castro
PAIVA, Gerson Silva
SOUZA, Ivone Antônia de
Fecha de publicación : 27-jun-2013
Editorial : World Intellectual Property Organization (WIPO)
Resumen : The present invention relates to oncology, in particular to a molecular compound denominated here as "oncoloose", which is capable of selectively destroying solid tumour cells without affecting rapidly replicating healthy cells. The present invention provides a product comprising a molecular compound denominated oncoloose, which is selectively targeted to the interior of tumours by means of a carboxylic group that neutralizes the negative electrical charge thereof, for transporting the acridine drug to the DNA in the tumour cells, preventing the replication thereof and causing apoptosis or cellular self-destruction of the tumour cells.
URI : https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2013091052
https://repositorio.ufpe.br/handle/123456789/61796
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